Clinical Effectiveness of Extracorporeal Membrane Oxygenation (ECMO) - A Systematic Review and Meta-Analysis

The review mainly focuses on the goals to evaluate the viability of ECMO in a decrease of mortality, length of stay, and other complications in adults above 18 years. Introduction: Inclusion criteria: This review is conducted in adult patients above 18 years who were included with cardiac or respiratory failure, or both. Respiratory, Neurological disease, Cardiac arrest, acute respiratory distress syndrome (ARDS), COVID-19, Haemorrhagic Stroke, Pneumonia, Bleeding, Renal replacement therapy, organ Failure primary graft dysfunction following lung Transplant, H1N1 Influenza, and other comorbidities. Methods: The databases of web indexes like PubMed, Google researcher, and Cochrane were utilized for this review. The titles and abstracts are screened and evaluated based on the inclusion criteria of the review. Depending on inclusion criteria the full-text articles were assessed exhaustively and chosen studies were recovered by methodological quality. Results: In this review among the retrieved articles forty-six studies met the inclusion criteria and those studies were pooled statistically and their outcomes were measured. All those studies explain the effectiveness of ECMO by reducing mortality, length of stay, and other complications. Conclusion: Currently with limited evidence suggests that ECMO reduces mortality, length of stay, and other complications in adult patients with respiratory, cardiac failure, and other comorbidities.