Medicaments Used in the Treatment of Periradicular Diseases: A Review of Literature

The success of endodontic therapy is based on the triad of mechanical debridement, through disinfection and a three dimensional obturation. The ethics of reasonable endodontic therapy are focused on prevention, minimization and elimination of infection which are not easy tasks within the condition of a root canal system. The endodontic protocols have evolved with the advent of modern endodontics. Usually the treatment of teeth with vital pulp is done in a single visit, eliminating the need for interappointment dressings. The need for intracanal medicament becomes more relevant in cases of pulp necrosis and periapical pathosis whose treatment is challenging due to the presence of biofilms and complex canal anatomy. The selection of an appropriate medicament plays a vital role. It is often even recommended to use two preparations either in combination or in sequence. The final aim is to achieve a full range of therapeutic effects. The following literature is to review the medicaments that are used in the treatment of periradicular diseases.