Hemophilia or “Royal Disease”
Journal: Journal of Pharmacy and Pharmacology (Vol.8, No. 5)Publication Date: 2020-04-30
Authors : Kourkouta Lambrini; Koukourikos Konstantinos; Iliadis Christos; Ouzounakis P.; Tsaloglidou Areti;
Page : 137-142
Keywords : ;
Abstract
Introduction: Hemophilia is an inherited sex-linked and life-threatening disorder of hemostasis, preventing proper blood coagulation due to the absence of a specific coagulation factor. Purpose: The purpose of this study is to review all data related to hemophilia disease. Material and Methods: The study material consisted of recent articles on the topic found mainly in valid databases such as PubMed and the Hellenic Academic Libraries Association (HEAL-Link). Results: For patients with hemophilia there is no damage to the original hemostasis function (where platelets are mainly involved), but the fault lies in coagulation. As such, flow time testing and in vivo monitoring of platelet function are completely normal. Consequently, a simple slip that happens to everyone does not lead to hemarthrosis—since initial hemostasis is normal—the same happens to hemophilic patients. Conclusions: Proper collaboration of the therapeutic team with the patient in conjunction with an individualized treatment program adapted to the needs of each patient and especially the child leads to effective improvement of the hemophilic patient.
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