Basics of Molecular Oncology! Radiation Oncologist Perspective!!

The process by which normal cells become progressively transformed to malignancy is now known to required the sequential acquisition of mutations which arises as consequence of damage genome of cells this damage can occurs as a result of endogenous process such as, The replications of DNA by free radicals generated during metabolic process, DNA can also get damage by external agents such as ionizing radiations ultraviolet rays as well as chemical carcinogens ,The new discipline by precisely identifying the molecular basis of differences between normal and malignant cells. The new concepts of cancer management by targeted therapy alone as well as along radiotherapy further makes this very important to understanding by oncologist specially radiation oncologist since targeted therapies to target altered genes and if goes a step ahead to specific targeted therapies for specific types of mutations happened in DNA.