In Vitro Hepatoprotective Activity and Qualitative Phytochemical Analysis of "Kamalaiku Chooranam" - A Siddha Formulation

Liver is the major and important organ which undergoes damages frequently by many causes. Liver has the ability to repair and regenerate by itself. Once it crosses the limit damage can't be reversed so the liver health has to be preserve for that purpose many herbals and herbomineral drug, are used to treat the disease and to protect from diseases before it exists. Jaundice is a very common symptom especially in the developing countries. It is associated with several hepatic diseases which are still major cause of death. There are many different approaches to jaundice treatment; many medicinal plants are used for the treatment of jaundice. The liver performs a vital role in metabolism, secretion, storage and detoxification of endogenous and exogenous substances, oxidative stress and free radicals enhances the severity of hepatic damage which can be overcome by the oxidative mechanism. Plant extracts can be the best source of such antioxidents and mediate hepatoprotective activity. These include "KAMALAIKU CHOORANAM" is the effective remedy for jaundice. Objective: The main objective of the study is to evaluate the hepatoprotective and biochemical activity and the biochemical analysis of kamalaiku chooranam. Methodology: Kamalaiku chooranam has its reference in literature of Anubhava vaiddya murai by C.N. Kuppuswami. The present study was undertaken to evaluate hepatoprotective activity of kamalaiku chooranam by using serial dilution of test formulation KMC [50, 100, 200 and 400ug/ml] were prepared using DMSO. Result: The study result was concluded that the drug kamalaiku chooranam has got significant hepatoprotective activity.