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Structural, Characterization, and Biological Activity of Novel Schiff Base Ligand Derived from Pyridoxal with 2-Aminobenzothazol and Its Complexes

Journal: Chemical Methodologies (Vol.6, No. 12)

Publication Date:

Authors : ; ;

Page : 1007-1022

Keywords : Pyridoxal 2; aminobenzothazol FT; IR UV; Vis;

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Abstract

A [VO(II), Mn(III), Fe(II), Co(II), Ni(II), Cu(II), and Pt(IV)] complexes prepared from 4-((benzo [d] thiazol-2-yl imino) methyl)-5- (hydroxymethyl)-2-methylpyridin 3-ol, ligand (HL1) Schiff bases is newly synthesized which is derived from the reaction between one equivalent of (pyridoxal hydrochloride) and one equivalent for (2-aminobenzothiazole). Multiple techniques and devices were used to diagnose the prepared compounds. Among these techniques are Melting Point Measurements, Fourier Transform Infrared Spectra, Conductivity Measurements, Electronic spectra UV-Vis., Mass Spectroscopy, Metal Analysis, Elemental Microanalysis, Magnetic Moment Measurement, Thermal Gravimetric Analysis TGA, 1H, and 13C-NMR Spectra. Then, it was measured the biological activity of the prepared compounds against four types of bacteria (Klebsiella pneumoniae and pseudomonas) (G-), (Staphylococcus aureus and bacillus subtilis) (G+), and a one type of fungus (Candida albicans).

Last modified: 2022-09-19 04:25:32