Evaluation of Rats’ Biochemical Markers in Artemisia Annua Linn. Extract After Lead Toxicity

This research aimed to evaluate the impact of Artemisia annua L. (A. annua L.) on liver and kidney functions following lead-induced injury that was extracted from the plant by using ethanol. Forty male rats were divided into 4 classes (ten rats per group), G1 called negative regulation, G2 administered 15 mg/kg of lead acetate per day for 15 days orally, G3 administered A. annua L. extract at 100 mg/ml IP for 2 weeks, and G4 administered 15 mg/kg of lead acetate per day for 15 days, and then handled A. annua L. at (100 mg/kg b.wt) for two weeks. As a result of the procedure, blood samples were aspirated for serum isolation, the serum was used to estimate alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine, and Urea. The present findings showed a significant (P≤0.05) increase in levels of AST and ALT in G2 compared with G1 and G3 which showed normal values, while G4 showed a significant decrease in ALT and AST levels as compared with G1 and G3, whereas G4 displayed a significant (P≤0.05) reduction popular levels of urea, creatinine G 2 related to G1 and G3 which revealed normal values.