RESULTS OF TREATMENT OF RIFAMPICIN-RESISTANT TUBERCULOSIS IN FEMALES WITH ALCOHOL DEPENDENCE SYNDROME

Background. Tuberculosis is still one of the urgent medical and social problems and poses a threat to human health around the world. Purpose of work: To study the features of rifampicin-resistant tuberculosis in male and female patients with alcohol dependence syndrome. Material and methods. The subjects were 219 patients with active rifampicin-resistant pulmonary tuberculosis and a diagnosis of alcohol dependence syndrome. During the study, two groups of patients were formed: group I – the main group (n=33) – included females with rifampicin-resistant pulmonary tuberculosis and alcohol dependence syndrome, group II – the comparison group (n=186) – was composed of males with rifampicin-resistant pulmonary tuberculosis and alcohol dependence syndrome. Results. Termination of bacterial excretion, confirmed by the bacteriological method, was obtained in 60.6% of the patients in the main group and in 57.2% of the patients in the comparison group (p>0.05). The analysis of radiological data (plain chest radiograph, linear tomogram) showed that closure of the decay cavities in the lungs was observed only in 6 (28.6%) and 50 (49.1%) cases (p<0.05), respectively. Conclusions. The modern social picture of rifampicin-resistant tuberculosis is represented by working-age individuals suffering from alcohol dependence syndrome, those who are not employed, women of reproductive age.