Drug Treatments in Development for Pemphigus Vulgaris (Pv) - A Review

New therapies are needed to combat the symptomatic underlying disease processes in the pemphigus vulgaris (PV). The author examine the rapid increase in the management of disease by using systemic corticosteroid have dramatically reduce complication of the disease, current therapeutic options are limited by toxicity profiles. In this review, potentially new symptomatic and disease modifying therapies will be described. We undertook a review of observational study of intervention which could reduce the burden of PV, particularly in low income and middle income countries. So we identified several interventions which sufficient evidence to recommend implementation in health system, including calcium supplementation with the corticosteroid. The most promising novel treatment includes KC706, a p38 mitogen active proteinkinase (p38 MAPK) inhibitor. The pharmacological treatments for disease continue to change, with many exciting possibilities for the future