Anticancer and Other Therapeutic Effects of Rosemary
Journal: International Research Journal of Pharmacy and Medical Sciences (IRJPMS) (Vol.6, No. 1)Publication Date: 2023-01-15
Authors : Bhartesh S. Shirdhone Alpesh S. Patil N. B. Chougule Bhadalekar M.V. Bhosale;
Page : 40-44
Keywords : ;
Abstract
Cancer cells have accelerated growth rates and resistance to apoptosis. Cancer cells develop the capacity to resist homeostasis, proliferate uncontrolled, and avoid programmed cell death/apoptosis due to mutations in important signalling molecules that control the pathways involved in cell survival and proliferation. Recently, the European Union (EU) and the Food and Drug Administration in the United States both approved rosemary extracts that were standardised to diterpenes (such as carnosic acid and carnosol) (FDA). The possibility of exposure to rosemary's diterpenes has increased as a result of its use in our food system and dietary choices (such as the Mediterranean Diet). According to reports, diet, especially consumption of vegetables and specific plant substances, plays a significant influence in lowering the chance of developing cancer. The ubiquitous household plant rosemary, which is grown all over the world, has recently attracted a significant amount of scholarly interest. Additionally, colon and prostate cancer xenograft in mice were suppressed by the rosemary extract and diterpenes. Compared to diterpenes, rosemary extract is more cytotoxic since it contains polyphenols like triterpenes and flavonoids. As a natural food preservative and therapeutic agent in the treatment of numerous diseases, Rosmarinus officinalis shows great promise. Several compounds known to be potent antioxidants are present in both the essential oil and extract of rosemary. The antioxidant activity of rosemary is essential to many of its biological activities. simply given that oxidative stress is a serious consequence of both diabetes and cancer, this is particularly true of rosemary's anti-diabetic and anti-cancer processes
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