Atrial Autonomic Denervation for The Treatment of Longstanding Symptomatic Sinus Bradycardia: A Case Report |Biomedgrid

A 56-year-old man with symptomatic sinus bradycardia (SB) of 5 years accepted the suggestion of atrial autonomic denervation. Radiofrequency pulses were delivered on atrial ganglionated plexi (GP) with positive vagal reflex according to the standard of heart rate (HR) drop ≥20% after high frequency stimulation (HFS). The endpoint of inexistence of HR decrease at repeating HFS was achieved in 16 sites. After 12 months of follow-up, the patient continued to have normal 24-hour total heart beats and mean heart rate and SB-related symptoms substantially improved. Autonomic denervation in LA and RA by endocardial ablation of GP may increase sinus rate and improve symptoms in non-elderly patients with symptomatic longstanding SB.