Sildenafil Slows Gastric Emptying in Patients with Previously Diagnosed Diabetic Gastroparesis |Biomedgrid

Journal: American Journal of Biomedical Science & Research (Vol.11, No. 3)

Publication Date: 2020-12-15

Authors : Imaneh Fallahi; Susannah T Clark; Suzanne Emil; Robert J Telepak; Mark R Burge;

Page : 252-257

Keywords : Diabetic Gastroparesis; Sildenafil; Therapeutics; Mechanisms of Disease; Complication;

Source : Download Find it from : Google Scholar

Abstract

Objective: Delayed gastric emptying is a common complication of diabetes. Animal studies suggest that inhibition of phosphodiesterase type- 5 receptors with sildenafil improves pyloric nitric oxide availability and reverses gastroparesis in murine models of diabetic gastroparesis. We hypothesized that a single dose of sildenafil would improve gastric emptying in diabetic subjects with gastroparesis.

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Sildenafil Slows Gastric Emptying in Patients with Previously Diagnosed Diabetic Gastroparesis |Biomedgrid

Abstract

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