Effect of Circadian Rhythm - Autonomic Nervous System - Endocrine Hormone Axis on The Occurrence and Development of Diabetes: A Review and Perspective |Biomedgrid

There are obvious circadian rhythms in organisms. In modern society, circadian rhythm disorders can be caused by factors such as shift work, staying up late for a long time, outbound tourism, psychological stress, various diseases and so on, and the disorders will regulate the physiological and biochemical functions of various tissues and organs through the autonomic nervous system, including the secretion and release of hormones, and then affect the occurrence and development of the disease further. At present, diabetes has become the sixth leading cause of death, and gradually tends to be younger. Considering the effects of systematic and holistic changes, such as circadian rhythm, autonomic nervous system and endocrine hormones, on the occurrence and development of diabetes, this paper summarizes the regulation of circadian rhythm-autonomic nervous system-endocrine hormone axis to blood glucose metabolism in order to find a new pathogenesis of diabetes and provide a new drug target for the treatment of diabetes.