UNVEILING THE POTENTIAL OF THERAPEUTIC MESENCHYMAL STEM CELLS IN CANCER TREATMENT
Journal: International Journal of Advanced Research (Vol.11, No. 6)Publication Date: 2023-07-01
Authors : Sindhu Mulpuri Sai Bhavani Venkatesh Pasupuleti Salma Shaik Rithvik Chalasani Bhargav Kothapalli; Reethika Singh Ranwas;
Page : 902-906
Keywords : MSC Pro-Apoptotic Factors Anti-Proliferative Agents Targetted Therapy Tumor Micro Environement;
Abstract
Recent studies have suggested that MSC (mesenchymal stem cells) can migrate to tumor specific regions and stem cell based therapies have potential in treating several cancers. Such cells are genetically modified to express certain pro-apoptotic factors, pro-drugs, anti-proliferative agents, therapeutic proteins, and anti-angiogenic agents at the tumor sites. It is also evident that new modalities of cancer therapies are needed immediately which would push this research to the clinic and render MSCs as potential vectors for targeted therapy. The current review focuses on different sources of mesenchymal stem cells used against tumors, the interactions and behavior of MSCs in the tumor microenvironment, and the usage of mesenchymal stem cells as delivery vectors.
Other Latest Articles
- ETUDE DUNE PHOTOPILE BIFACIALE AU SILICIUM EN REGIME STATIQUE SOUMISE A UN CHAMP MAGNETIQUE SOUS ECLAIREMENT MONOCHROMATIQUE PAR LA FACE ARRIERE: DETERMINATION DE LEPAISSEUR OPTIMUM DE LA BASE
- SARCOME DU STROMA ENDOMETRIAL :LOCALISATION SECONDAIRE GASTRIQUE INHABITUELLE A PROPOS UN CAS AVEC REVUE DE LA LITTERATURE
- STUDY ON EMERGENCE OF MDR PATHOGEN AND ITS MICROBIOLOGICAL STUDY
- GLYCAEMIC CONTROL AMONG SAUDI PATIENTS WITH TYPE 2 DIABETES MELLITUS AT FIRST TIME REGISTRY IN RAQEB RECORDS FROM 2018-2022
- DETECTION AND QUANTIFICATION OF BIOFILM FORMED BY CANDIDA SPECIES ISOLATED FROM CLINICAL SAMPLES AT TERTIARY CARE HOSPITAL
Last modified: 2023-08-01 15:27:12