Effectiveness, Safety and Tolerability of Intravaginal Prasterone for the Treatment of Genitourinary Syndrome in Postmenopausal Women in Spain: The Estip-Es Study |Biomedgrid

Genitourinary syndrome of menopause has a significant and negative impact on quality of life. The objective of this study was to evaluate the effectiveness, safety, and tolerability of prasterone for the treatment of genitourinary syndrome in clinical practice in Spain. We performed a prospective, observational, and multicenter study in adult postmenopausal women. Female Sexual Function Index (FSFI) questionnaire and Visual Analog Scale (VAS) were administrated and level of satisfaction was analyzed at baseline and after 30±7 days. The study included 184 postmenopausal women with genitourinary syndrome. The FSFI increased from 15.7±6.3 to 19.9±5.38 (P<0.01), with significant improvements in all items.