A Review on Long Term Chronic Toxicity Study
Journal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.8, No. 10)Publication Date: 2023-10-30
Authors : Shivkanya Mhaske; Shivprasad Mhaske; Amrapali Pagare; Nikam Harshda;
Page : 107-116
Keywords : Sub chronic toxicological assessment; Biochemical; Hematological and Histopathological changes;
Abstract
Toxicity study of a new drug compound is an essential step in the process of new drug development. Long term toxicity testing is done on various biological systems. Dose specific toxic effect on vital organs of an investigational products is essential. After the acute toxicity testing, sub chronic toxicity can be proceeded by studying the assessment of an investigational product on morphological, behavioral, biochemical, haematological and histopathological parameters on experimental animals.
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