Kinetochore, An Anchorage Site for The Dividing Chromosomes, Helps Maintain the Integrity of The Genome Over Generations |Biomedgrid

The continuity of life on this planet owes a lot to the efficient cell division of all organisms which in turn supports the survival of these organisms. During cell division, the chromosomes, a thread-like structure made of nucleic acid and proteins need to get duplicated before entering the actual division phase where the sister chromosomes are separated to ensure faithful distribution of genetic make-up among the progeny. This segregation/distribution of chromosomes is mainly regulated by kinetochore besides helping the cells avoid mis-segregation. In this mini review, we will briefly follow up the studies undertaken for a molecular mechanism involving the functions of kinetochore and will try to suggest what areas are more important to investigate than others regarding the cell cycle.