Cold chain in pharmaceutical logistics, ensuring the quality and safety of medicines

Ensuring the quality and safety of medicines is a key factor for effective treatment and prevention of undesirable consequences. For many medicines, especially biologics, vaccines and some chemotherapeutic agents, it is extremely important to maintain a strictly defined temperature regime throughout the entire supply chain, from production to the end user. This is due to the fact that temperature deviations can lead to degradation of active substances, changes in the physico-chemical properties of drugs, a decrease in their effectiveness and even the appearance of toxic impurities. In this paper, we will consider the key aspects of the cold chain in pharmaceutical logistics, which includes a set of measures to ensure the proper storage and transportation of medicines in need of a strict temperature regime.