ROLE OF CRP, WBC COUNT AND USG ABDOMEN IN THE DIAGNOSIS AND EVALUATING THE SEVERITY OF ACUTE APPENDICITIS

Introduction:Modern imaging and lab testing may not always provide a definitive diagnosis for the most common cause of acute abdomen in young adults: acute appendicitis. In an effort to decrease needless appendectomies and enhance results, this study matches histology, CRP, leukocyte count, neutrophil count, and ultrasonography to determine the best reliable diagnostic test. Methods:In a study of 50 acute appendicitis patients scheduled for appendectomy, TLC, differential count (neutrophil count), CRP, and USG abdomen were evaluated for diagnostic accuracy alongside histopathology. Statistical analysis included descriptive and inferential methods, with continuous data as Mean ± SD and categorical data in percentages, assessing significance at 5%. Result:92% of the 50 patients who had acute appendicitis had pain that moved from the periumbilical area to the right iliac fossa most of these patients were between the ages of eleven and twenty. It was more usual for men to have acute appendicitis (76 %). Higher leukocyte counts (52 %), neutrophil counts (48 %), and CRP levels (62 %) were seen in the laboratory high sensitivity (95.56%) and low specificity (20.00%) of ultrasound, indicating a good but sometimes false-positive detection rate of appendicitis. High PPV (100%) and specificity (100%) were exhibited by Total Leukocyte Count, but low accuracy (57.78%) and sensitivity were noted (62.00 %). Low NPV (15.38 %) and accuracy were observed in Neutrophil Count, despite moderate sensitivity (51.11 %) and high PPV (95.83 %) (54.00 %). With a high PPV (96.77%), moderate accuracy, and balanced sensitivity (66.67 %) and specificity (80.00 %), CRP was provided (68.00 %). 90 % of cases had histopathology confirm that they had acute appendicitis. Conclusion:The study assesses diagnostic procedures for acute appendicitis in individuals experiencing pain in the right iliac fossa. TLC exhibits excellent specificity (100%) but poor accuracy and sensitivity (57.78%). (62 %). The sensitivity and accuracy of CRP and neutrophil counts are moderate. USG has a low specificity (0.05%) but a high sensitivity (95.56%). (20 %). Reducing negative appendectomies and improving diagnostic accuracy are achieved by combining TLC, neutrophil count, CRP, and USG.