Effect of cornus fruit extracts on oxidative stress in diabetes

The biological effects of fruits from different cultivars of the cornelian cherry under diabetes mellitus remain unclear. Aim. This study was purposed to investigate the effect of fruit extracts from various cultivars of Cornus mas L. on primary biomarkers of oxidative stress. Materials and Methods: oxidative stress metabolites in erythrocytes were assessed by measuring the level of lipid peroxidation and protein oxidation products. Results. The administration of C. mas and C. mas  C. officinalis hybrids fruit extracts to diabetic rats significantly reduced oxidative stress metabolite levels in erythrocytes. Conclusions: сornelian cherry fruit extracts are perspective drugs that help inhibit oxidative stress development in erythrocytes under diabetic conditions.