Effect of Dosha Dushya Sammurchchhana in the Pathogenesis of Disease

According to Ayurveda, Tridosha, Saptadhatu, Trimal are fundamental factors of the body. 1 Ayurveda is a science that deals with both the therapeutic and preventive aspects of human health . Dosha Dushya Sammurchchhana is important in the aetiology of disease that are of major relevance in both the therapeutic and preventive aspects. Vyadhiutpatti has been considered as the process of disease manifestation. It consists of consecutive stage of pathogenesis resulting into disease. Knowledge of Khavaigunya explains how the vitiated Doshas stagnates in a particular part of the body to produce disease, leaving aside other part of the body. Here the present study is the review of our classical Ayurveda text that includes concept of Shatkriyakala, detailed explanation of Strotodushti and its types, explanation of Khavaigunya and Dosha Dushya Samurchchhna in the manifestation of disease. Dr. Saurabh Suryakant Barkule | Dr. Amol Kamthe | Dr. Nandlal Topandas Kundnani | Dr. Pournima Barkule (Kadam) "Effect of Dosha-Dushya Sammurchchhana in the Pathogenesis of Disease" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-10 | Issue-1 , February 2026, URL: https://www.ijtsrd.com/papers/ijtsrd100065.pdf Paper URL: https://www.ijtsrd.com/medicine/ayurvedic/100065/effect-of-doshadushya-sammurchchhana-in-the-pathogenesis-of-disease/dr-saurabh-suryakant-barkule