METHOD DEVELOPMENT FOR ESTIMATION OF ALCOHOL IN AYURVEDIC FORMULATIONS USING GAS CHROMATOGRAPHY

Marketed herbal preparations containing self generated alcohol (herbal origin and allopathic) may affect the health of patients on faulty dosing. The method was set up for the quantitative estimation of alcohol by gas chromatography. The method was developed by changing various parameters of gas chromatography. Furthermore, the method was validated in order to confirm its reliability and potentials to use as quality control tool in QC laboratories. In ayurvedic preparation arishtha, the estimated alcohol (as self generated alcohol) was found to be 8.1% (khadirarishta), 10.2% (drakshakumari), 7.8% (saraswatarishta) and obeyed the label claim. The present work can be used as the method for routine quality and safety standardization.