DIAGNOSTIC AND PROGNOSTIC EVALUATION OF IMMUNOHISTOCHEMICAL MARKERS OF INTESTINAL METAPLASIA OF THE GASTRIC MUCOSA

The expression of molecular and biological markers in the intestinal metaplasia (IM) of the gastric mucosa on the basis of pathomorphological analysis was studied. It is shown that the follow useful prognostic and diagnostic value have been used: differentiation of intestinal transcription factor (CDX2), cytokeratin 7 (CK7), mucin (MUC 5 AC) and a marker of proliferative activity ? Ki-67. The algorithm for pathomorphological diagnosis of gastric mucosa IM with using of immunohistochemical markers was suggested.