AN OVERVIEW: SITE SPECIFIC DRUG DELIVERY SYSTEM

The drug delivery system is to provide a therapeutic amount of drug to a proper site in body so that the desired concentration can achieved promptly and then maintained. Site specific drug delivery refers to targeting a drug directly to a certain biological location. Targeted drug delivery implies selective and effective localization of drug into the target at therapeutic concentrations with limited access to non target sites. Recently, greater emphasis has been placed on controlling the rate and or site of drug release from oral formulations for the purposes of improving patient compliance and treatment efficacy. Benefits of site specific drug delivery Drug directly available at the target site, Decrease in dose to be administered, Decrease side effect, improve drug utilization; it is a promising site for drugs which are unstable or poorly absorbed at upper GI tract. It is a challenging task to formulate such kind of drug delivery system. Keywords: targeted drug delivery, site specific drug delivery, Pharmacokinetic, Pharmacodynamic, sustained drug delivery.