INFLUENCE OF DIPYRIDAMOLE AND ATP ON IMMUNOSUPRESSING PROPERTIES OF ERYTHROCYTES AND THROMBOCYTES IN EXPERIMENTAL NON - OBSTRACTIVE PYELONEPHRITIS

Investigations on 175 Wistar rats showed that thrombocytes of animals with non-obstructive pyelonephritis have possessed immunosupressing properties being increased on interaction with light erythrocytes and serum factors, accumulated in blood of rats with pyelonephritis. Introduction of dipyridamole and ATP blocked thromboerythrocyte chain of immunosuppression development in rats with pyelonephritis. Here, the pyridamole action was directed to thrombocyte - erythrocyte unit, and the ATP action - to light erythrocytes.