Comparative efficacy of drugs of different pharmacotherapeutic groups in experimental toxic hepatitis
Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.11, No. 1)Publication Date: 2010-02-28
Authors : Taouk A.N.; Fiodorov V.N.; Kunitsa Z.A.; Smirnov N.A.; Kotshneva N.V.;
Page : 66-73
Keywords : ;
Abstract
This article discusses the evaluation of pharmacological effectiveness of drugs of different pharmacotherapeutic groups in an experimental model of toxic hepatitis. The method of two-stage pharmacological screening. Key findings: of immunomodulators were found drugs worsen the condition of the liver against toxic hepatitis, the combination of essential phospholipids and glycyrrhizic acid is substantially more important hepatoprotective activity, in comparison with the effectiveness of this combination of components that are applied separately, the number of members of the group of adaptogens immunostimulant effect of which is the only one component of their actions, have a more pronounced hepatoprotective activity compared with the specialized immunomodulators
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