Matrix metalloproteinase-9 as a biomarker of poag
Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.13, No. 4)Publication Date: 2012-11-30
Authors : Sokolov V.A.; Levanova O.N.; Nikiforov A.A.;
Page : 139-142
Keywords : ;
Abstract
Diagnosis of primary open angle glaucoma (POAG) early stages of the pathological process remains a difficult task, even for experienced ophthalmologists. This work is devoted to the study of matrix metalloproteinase-9 (MMP-9) in lacrimal fluid of patients with POAG as a biomarker of this disease. Revealed a significantly higher concentration of MMP-9 in a lacrimal fluid in patients with glaucoma, at the initial stage of the pathological process. Dependence between levels of MMP-9 and stages of the pathological process has been established.
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