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PATHOGENETIC ROLE OF ENDOTHELIN-1 IN HEMORRHAGIC FEVER WITH RENAL SYNDROME

Journal: NAUKA MOLODYKH (Eruditio Juvenium) (Vol.4, No. 1)

Publication Date:

Authors : ;

Page : 12-16

Keywords : endothelin-1; locus rs 5370 polymorphism of endothelin-1 gene; hemorrhagic fever with renal syndrome;

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Abstract

A statistically significant decrease in the concentration of endothelin-1 in the dynamics of hemorrhagic fever with renal syndrome, depending only on the shape of its severity, is revealed. Role of endothelin-1 in the maintenance of systemic blood pressure of patients with hemorrhagic fever with renal syndrome is negligible. A polymorphic gene locus of endothelin-1 is not associated with the severity of the disease.

Last modified: 2016-04-19 22:33:53