Performance evaluation of safety and protection Isomaltooligosaccharide prebiotics in reducing histopathological common carp (Cyprinus carpio) of different concentrations Pretilachlor

Background and Aim: Herbicides have become one of the largest technology tools for agriculture. With the arrival of the body fish, can damage body organs and eventually be transferred to final consumer, means humans. According to the effects of isomalto-oligosaccharides prebiotic on, and some indicators of biological growth of aquatic species, in this study the effects isomalto-oligosaccharide prebiotics immune on liver, gills and intestines tissue at pretilachlor concentrations lethal poison in common carp. Materials and Methods: In this study, 147 common carp with average 6.13±0.31 were stored for about two weeks in aquariums to adapt to environmental conditions. Water physicochemical parameters were measured during the experiment. Four concentrations 2 mg/l, 2.4 mg/l, 2.8 mg/l, 3 mg/l of pretilachlor and 1 g/kg prebiotic isomalto-oligosaccharides were considered for this study. Results: The results showed that the probiotic treatments samples that exposed to Pretilachlor had some liver lesions: vacuolization, the degeneration of the epithelium, the destruction of the villi in the intestine, and ascites complications include hemorrhage, necrosis and stagnation of bile, hyperplasia symptoms of primary and secondary blade, blade coating of the secondary gill tissue. Conclusion: The results of this study showed that probiotic isomalto-oligosaccharides alone cause lesions in the liver, gills and intestines of common carp. As well as treatments before exposure to lethal doses of poison, immunated by probiotics isomalto-oligosaccharides, pretilachlor could not lead immune and safety against the damaging effects of pollution and these probiotics could be useful as safe and effective.