FUNCTIONALLY SUBSTITUTED TRIAZOLE PYRIMIDINE WITH OXO BASIS AND 2-AMINO-1,3-THIAZOLE

Under the ultrasound activation conditions with the three-component condensation (ethylacetoacetate, aromatic aldehyde, aminothiazol) there are not expected tiazolohinazoliny and tiazolopirimidiny as a result of the interaction of the intermediate α, β-unsaturated ketones with an aminating agent. Introduction to the ortho position of the benzene ring of the carbonyl group of the hydroxyl components leads to the formation of nitrogen-free compounds (chromene). Among the synthesized compounds, the compounds possessing interesting algal activity against the green alga Dunaliella salinaTeod are detected.