A TERTIARY CARE HOSPITAL EXPERIENCE OF NON CLEAR CELL RENAL CELL CARCINOMA

Renal cell carcinomas are a heterogenous group of tumours with varying prognosis. Most common histological type is clear cell variant constituting about 60 70 of all cases. The rest comprises a mixture of tumors of different histological types. Hence in this study we aimed to evaluate the clinical and histomorphological features of non -clear cell renal cell carcinomas. Among renal cell carcinomas diagnosed over a period of 6 years and two months, 40 cases (28.5) fell into the category of nonclear cell type. They included papillary, chromophobe, sarcomatoid, unclassified and collecting duct carcinomas, each constituting 16.4 , 3.5 , 5, 2.2 and 0.7 percentage respectively. Clinically most of them presented in Stage III and histologically most of them belonged to Fuhrman nuclear grade 2. Histological subtype, tumour staging, nuclear grading and microvascular invasion are useful for determining the prognosis, adjuvant therapy and for followup.