MOLECULAR MECHANISMS OF ALCOHOL INTOXICATION

The state of the main neuromediator systems of the brain as well as indicators of carbohydrate exchange in the liver and skeletal muscles of rats under the main manifestations of experimental alcoholism ? acute and chronic alcohol intoxication, as well as alcohol withdrawal syndrome ? have been investigated. Disorders of catecholamine neuromediation in the thalamic area and in the trunk, as well as those of glycolysis and the pentosophosphate pathway in tissues have been revealed. The received results make an essential contribution to the interpretation of molecular mechanisms of alcohol intoxication.