Radiation induced carcinosarcoma of the skin - a case report

Sarcoma developing within the field of the radiation (Radiation induced sarcoma - RIS) is a late effect of ionising radiation. Multi-agent treatment including chemotherapy and radiation are being increasingly included in the treatment of cancer. RIS is an uncommon tumour with an incidence of less than 1 for patients with cancer who are treated with radiation and survive 5 years1. Little doubt exists that the benefits of ionizing radiation far outweigh the potential risks of developing sarcomas. Due to paucity of experience and literature of this rare tumor, the optimal management is not standardized and the role of adjuvant radiation and chemotherapy is not defined. However local, regional and distant recurrences have been seen and treatment seems best judged by the clinical presentation.This case has been presented for its rarity and for being the first documented case of a carcinosarcoma arising in previously radiated skin.