Antibacterial Activities of Palladium (II) Complexes Derived from Chitosan Biopolymer Schiff Base

Chitosan is a biopolymer, contains polymeric amine which can be modified chemically by condensation reaction with aldehyde in homogeneous phase. This polymeric primary amine (-NH2) of chitosan is functioning for the chemical modification with 4-hydroxy-3-methoxy benzaldehyde, and 2-hydroxy benzaldehyde to form corresponding schiff base derivatives. This schiff base derivatives are becomes a complexing agent or ligand. The Palladium (II) complex was obtained by complexation of Palladium with schiff base ligands and this product exhibits as an excellent solubility and more biocompatibility. The novel series of schiff base Palladium (II) complexes were characterized by Elemental analysis, spectral analysis to confirm the structure and functional groups of chitosan schiff bases, also their metal complex. The synthesized complex has been subjected to antibacterial study. The synthesized chitosan schiff base metal complexes are showed significant antibacterial result against pathogenic bacteria. These findings are giving suitable support for developing new antibacterial drugs and this has motivated us to expand our research and scope for applications.