Impact of Gestational Diabetes Mellitus (GDM) on the Platelet Activity and Coagulation System

This study aims to identify the effect of gestational diabetes mellitus on platelet indices and the coagulation system. Although the mechanism for GDM is unclear, numerous studies have been conducted to determine the correlation between GDM with different immunological factors. A systematic literature review will be conducted herein to assess the influence of GDM on the immunological factors that result in pregnancy complications and adverse pregnancy outcomes. Results for the survey indicated that GDM is associated with altered coagulation systems that may result in hypercoagulability, resulting in bleeding. The report also showed that GDM is linked to increased platelet and inflammatory indices, which predispose pregnant women to vast pregnancy complications. Therefore, the study concluded that even though the mechanism of GDM is unknown, various factors influence its incidence, including altered coagulation systems and increased platelet indices.