To Study Neutrophil to Lymphocyte Ratio and Platelet - Lymphocyte Ratio in Patient with Rheumatoid Arthritis

Introduction: Rheumatoid arthritis (RA) is a chronic and systemic autoimmune diseases with synovial joints inflammation; that culminate into progressive damage of joint, especially with persistent inflammation. Rheumatoid arthritis signs and symptoms may vary in severity and may even come and go. Aim and Objective: To determine any association between NLR, PLR, and RA. Material and Methods: This was a Hospital based, cross-sectional and comparative study. This study was conducted at SMS Medical College and Hospital (Department of Medicine), Jaipur, Rajasthan, India. Data collection was started after approval from institutional research review board to April 2021 and another 2 months were required for the write up. Sample size was calculated to be 30 subjects in each group. Result: Sample size was calculated to be 30 subjects in each group. Mean age of RA cases was58.03 ? 15.69 years, while that of Controls was 57.87 ? 15.59 years. Most of the RA Cases were females (63.3%), while only 11 cases (36.7%) were males. The mean hemoglobin level was slightly higher among RA cases (12.37 ? 2.48 g/dl) as compared to controls (11.6 g/dl). The mean TLC count was higher among RA cases (7.77 ? 3.86 x103/cumm) as compared to controls (5.7 ? 1.76 x103/cumm). Conclusion: Neutrophil lymphocyte ratio and platelet lymphocyte ratio were significantly associated with Rheumatoid arthritis. They can be obtained via complete blood count, which is convenient, inexpensive, and fast. Therefore, the NLR and PLR is especially suitable for peripheral centers and can serve as an additional useful marker for the diagnosis of RA.