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The morphometric parameters of non-parenchymal liver cells of 6–12-months old dead children from HIV-mono-infected mothers

Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.52, No. 52)

Publication Date:

Authors : ;

Page : 69-80

Keywords : HIV liver Kupffer cells hepatic stellate cells liver-associated lymphocytes;

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Abstract

Background. HIV infection remains one of the most pressing global medico-social challenges, affecting all age and social groups, including newborns and infants born to HIV-infected mothers. Despite the considerable amount of research dedicated to adult HIV-infected populations, data on the morphofunctional changes in the liver of infants within the first year of life remain limited. Of particular interest is the study of non-parenchymal liver cells – Kupffer cells, hepatic stellate cells, dendritic cells, and liver-associated T-lymphocytes – which play a crucial role in maintaining hepatic immune homeostasis.

Last modified: 2025-05-25 01:14:13