ACUTE PURULENT PYELONEPHRITIS (REVIEW). PART II – TREATMENT

Acute purulent pyelonephritis is a serious disease that requires adequate treatment, since without it, severe complications are possible, including sepsis and septic shock with high mortality. Traditionally, the main method of treating acute purulent pyelonephritis was open surgery, but in recent years there has been a transition to more modern and less invasive methods, such as endovideosurgical operations, which provide faster rehabilitation and shorter hospital stays. After surgery, patients are prescribed empirical antibacterial therapy to achieve a high concentration of antibiotics in the renal tissue. However, despite advances in treatment, there remains a high incidence of complications, such as urosepsis and acute renal failure, which leads to the need for nephrectomy and high postoperative mortality. It is also important to take into account the resistance of microorganisms to antibiotics, which requires an individual approach to the choice of therapy. Modern approaches to the treatment of acute purulent pyelonephritis include not only surgical methods, but also extracorporeal methods of detoxification and drug immunocorrection. Restoration of urine outflow from the affected kidney is critical for successful treatment, as it improves the effectiveness of antibacterial therapy. It is important to continue research to optimize treatment methods and determine the best time for surgical intervention, which can help preserve kidney function and improve patient outcomes.