A STUDY OF ATTENUATION OF HEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION USING INTRAORAL IVABRADINE
Journal: International Journal of Advanced Research (Vol.13, No. 04)Publication Date: 2025-04-27
Authors : Suma M.;
Page : 1165-1170
Keywords : Ivabradine Hemodynamicresponse Laryngoscopy Endotrachealintubation Sympatheticstimulation Heartrateattenuation Intraoralpremedication Perioperativecare;
Abstract
Introduction: Laryngoscopy and endotracheal intubation provoke a sympathetic surge that results in transient but significant increases in heart rate and blood pressure. These hemodynamic responses can be detrimental in patients with cardiovascular comorbidities. Ivabradine, a selective I_f channel blocker, reduces heart rate without affecting myocardial contractility or blood pressure. This study was designed to evaluate the effectiveness of intraoral ivabradine in attenuating the hemodynamic response to laryngoscopy and intubation.
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