EMERGENCE OF NATURAL SUPERDISINTEGRANTS IN THE DEVELOPMENT OF ORALLY DISINTEGRATING TABLETS

Orally disintegrating tablets have carved a significant role amongst the oral drug delivery systems owing to their enhanced patient compliance especially in the geriatrics and pediatrics. These tablets offer numerous substantial advantages over conventional dosage forms because of improved efficacy, bioavailability and rapid onset of action. Use of natural superdisintegrants in the development of orally disintegrating tablets has numerous benefits such as chemically inert, non-toxic, less expensive, biodegradable and widely available. The present manuscript is an earnest attempt to illustrate ideal properties, significance and formulation aspect of orally disintegrating tablets especially the use of superdisintegrants. Various natural superdisintegrants utilized in the development of orally disintegrating tablets have also been discussed. Keywords: Orally disintegrating tablets, Natural superdisintegrants, Gums, Mucilages, Disintegration time