ISOLATION, SPECTRAL IDENTIFICATION OF QUERCETIN, AND DETERMINATION OF WOUND HEALING ACTIVITY FROM THE ALCOHOLIC ROOT EXTRACT OF CLERODENDRON INFORTUNATUM LINNJournal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.03, No. 08)
Publication Date: 2016-08-17
Authors : Leena.P.N; Sundaraganapathy;
Page : 814-820
Keywords : C. infortunatum; UV; IR; NMR; MASS spectroscopy.;
Plant materials are used throughout developed and developing countries as home remedies, over the counter drug products and raw materials for the pharmaceutical industry and represent a substantial proportion of the global drug market. It is therefore essential to establish internationally recognized guidelines for assessing their quality. Some of quality control parameters of the root Clerodendron species belonging to Verbenceae family were analyzed. It includes root powder characters, moisture content determination by LOD method, FOM determination, Rf value detection by TLC, using different solvents, Ashvalues, extractive values, bitterness value, Haemolytic activity, detection of tannins, Foaming Index, Detection of Arsenic and heavy metals, determination of micro organism. The isolation of the compound from the extract by coloumn chromatography by using different solvents ,purified ,analysed by various spectral studies . The study ensures that the quality control parameters do help in the proper standard of the crude drugs in drug development process for global acceptances. The current study may be useful to progress further investigation on the isolation of other flavanoids and their biological potential for the treatment of human ailments. Keywords: C. infortunatum,UV, IR ,NMR, MASS spectroscopy.
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