Microvascular complications of type 2 diabetes mellitus and Biochemical Parameters

Type 2 Diabetes mellitus is a chronic metabolic disease which is associated with increased morbidity and mortality. Long term diabetes is a risk for the development of microvascular complications which affect small blood vessels . Microvascular complications of diabetes include retinopathy, nephropathy and neuropathy producing blindness and renal failure if not treated early. The patients are to be screened regularly so as to prevent the complications or to reduce the progression of the complications. With this background the present study was undertaken to find out the possible role of biochemical parameters in patients with type2 diabetic microvascular complications. 50 type 2 diabetic patients were studied. They were tested for the presence or absence of microvascular complications. 25 healthy individuals were chosen as controls. Cases and controls were analysed after investigating their fasting blood glucose, fasting lipid profile, glycated Hemoglobin, blood urea, serum creatinine and urine albumin creatinine ratio.The analysis showed that patients with microvascular complications had hyperglycemia, longer duration of diabetes, dyslipidemia,and elevated albumin careatinine ratio compared to diabetics without complications and controls.Therefore these biochemical parameters can be used to assess the risk of microvascular complications development and also can be used to monitor progression in patients with complications