Wonderful Effects of Royal Jelly on Treatment of Male- Factor Related Infertility

Background: Royal jelly has been used since ancient time as a supplement for nutrition, anti-aging and infertility. In this study, we consider the effect of Royal jelly on male related factor infertility in rats. Materials and Methods: In this study we divided thirty 60-day-old male rats into two groups, control and case group. The case group gavaged 400mg/kg Royal jelly composed with honey once a day, while the control group underwent only honey. After 28 days, rats became unconscious and after blood sampling underwent bilateral orchiectomy and epididymal sperm aspiration. Then histological and hormonal evaluations were performed on samples. Results: Spermatogenesis, count and motility of sperms were significantly higher in case group comparing to the control group, also leydig cell count meaningfully increased in case group, while sertoli cell count had no difference in both groups. LH, FSH, and testosterone serum levels had no meaningful difference in both groups. Conclusion: We found that consumption of Royal jelly have a significant effect on sperm count and motility. It seems where there is idiopathic azoospermia, oligospermia and asthenospermia, the use of royal jelly is very effective and a significant help in treatment of infertility.