A RARE CAUSE OF GENERALISED LYMPHADENOPATHY

Sinus histiocytosis with massive lymphadenopathy (SHML) or Rosai- Dorfman syndrome is a rare benign proliferative histiocytic disease of unknown origin. It predominantly affects the lymph nodes. The head and neck region usually in association with lymph node involvement represents one of the most common extra nodal areas affected by SHML. The other common extra nodal site is skin.Rarely, there is wide spread dissemination with liver, kidney, respiratory organs, orbit, and eyeball involvement. The mean age of onset is 20 years (birth to 74 years).