Sex-determining region y (SRY)-Box2 (SOX2) & L1-cell adhesion molecule (L1CAM) expressions in endometrioid carcinoma of the uterus; An Immunohistochemical Study

Background: activation of cancer stem cells and disturbances in cell adhesion pathways are recently incriminated in endometrioid carcinoma progression, invasion and metastases which consequently leads to dismal patients outcome. Sex-determining region y (SRY)-Box2 (SOX2) is a member of SOX family and it has many roles in malignant stem cells control. L1-cell adhesion molecule (L1CAM) is a membrane glycoprotein which is a member of immunoglobulin family.