Mycophenolate Mofetil - Necessity of Monitoring of the Drug Level in Blood Patients after Kidney Transplantation

The authors, based on data from the literature and our own clinical experience, analyze the need for continuous monitoring of the levels of immunosuppressive drugs used in patients with renal transplant. They are convinced that the accurate and frequent determination of blood levels of calcineurin inhibitors, mTOR inhibitors, and in selected cases of mycophenolate mofetil, is now a necessity. Monitoring levels of MMF AUC method is particularly useful in optimizing the dose of the drug, and thus can contribute to a reduction in side effects and may minimize risk of rejection.