Infantile tremor syndrome- a case report

Infantile tremor syndrome is a rare clinical phenomenon, usually presenting with coarse tremors, anaemia, developmental regression and skin hyperpigmentation. Multiple vitamin and mineral deficiencies are attributed to its etiopathogenesis. We report an eight month old infant who presented to us with rythmic, coarse, oscillatory movements of the head and extremities, anaemia and dermal hyperpigmentation. The child had clinical and biochemical evidence for vitamin B12 deficiency. Tremors had subsided after parenteral high dose vitamin B12 therapy.