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ELECTRIC STIMULATION OF CEREBELLAR ARCHICORTEX INHIBITS THE RETINOPATHY SIGNS AT EXPERIMENTAL DIABETES

Journal: Science and world (Vol.3, No. 6)

Publication Date:

Authors : ;

Page : 152-156

Keywords : streptozotocin; diabetes retinopathy; superoxide dismutase; catalase; glutathioneperoxidase; glutathionereductase; malondialdehide; cerebellum.;

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Abstract

The retinopathy development after sugar diabetes was induced in Wistar rats via i.p. streptozotocin (50,0 mg/kg) administration was characterized by suppression of the activity of superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase, with the parallel elevation of the malone dialdehide content. Electrical stimulations of paleocerebellum (100 Hz, three times daily, during one month) effectively prevented the diabetesinduced decreasing of antioxidative enzymes activity and increasing of malone daldehide content.

Last modified: 2014-09-11 17:46:46