ANATOMICAL AND EXPERIMENTAL SUBSTANTIATION OF LIVER RESECTION BY HYDRODISSECTION METHOD

Background. In the situation of increasing number of surgical interventions on the liver, the use of new methods of its resection remains relevant and requires further study. Objective. To develop in the experiment a model of liver resection taking into account the features of intraorganic architectonics of tubular structures by using hydrodissection, the original device and various solutions. Material and methods. The anatomical part of the study was performed on 45 liver specimens of cadavers without liver pathology. The experimental part of the study was carried out on 24 rabbits using the original device and was followed by morphological study at 3, 14 and 30 days. Results. A signifcant variability of intraorganic architectonics of segmental vessels and ducts has been established,which should be taken into account when performing economical operations on the organ. Resection of the liver by hydrodissection with the use of liquid agents containing Emoxipine and Emoxipine/Chlorhexidine, and covering of the wound surface by omentum does not cause severe adhesions in the operation zone or exudative complications. Conclusions. Resection of the liver by hydrodissection using the original device and the proposed liquid agent, performed with due account of topography of the tubular structures of the organ, has a minimal damaging effect on the parenchyma in the area of operation and is promising for clinical use.