A Comparative Study of Tramadol Gargle and 2% Lidocaine Plain Solution for the Prevention of Postoperative Sore Throat Following General Anesthesia with Endotracheal Intubation in Patients Undergoing Cesarean Section

Background: postoperative sore throat has reported incidence of up to 12% following General anesthesia .in adults undergoing tracheal intubation, female sex, younger age preexisting disease of larynx and trachea, prolonged duration of anesthesia, traumatic intubation and the presence of a blood -stained tracheal tube on extubation are associated with greatest risk Aim of study: To compare between tramadol gargle and 2% lidocaine plain solution as regard their efficacy for controlling the postoperative sore throat after General Anesthesia with Endotracheal intubation. Patient and methods: 90 patient ASA class Il, Female, Age between (18-40), scheduled for Cesarean Section C/S requiring General Anesthesia with endotracheal intubation were randomly recruited into 3 groups: group A (tramadol), group B (2%xylocain plain solution), group C (tape water 30cc). Group A received tramadol gargle [ 100 mg in 30 ml tape water] for 2min, while group B received 2% plain solution lidocaine(2mg/kg) in 30 ml tape water gargled for 2min and group C received 30ml tape water was gargled for 2 min before induction of anesthesia. The incidence and severity of Postoperative sore throat were graded at 0,1,6 hr after surgery using four point -scale. Result: the incidence and severity of POST was significantly less in group A (tramadol group) in compared with group B (2% xylocaine plain solution) and group C (tap water) at grade zero,1hr. No statistically significant association (P= 0.108) between study groups and development of postoperative sore throat after six hours. Conclusion: study demonstrated that preoperative gargling with tramadol will decrease the incidence and severity of POST in compared to gargling with 2%xylocain plain solution in patient undergoing cesarean section during general anesthesia with endotracheal intubation in the early postoperative period.